When the reigning Italian Supersport champion crashed out on lap 3, it was the end of a promising weekend for Pirro, who suffered a broken nose, facial bruising and a fractured right wrist in the incident.
Pirro, whose best result this year has been a third place at Portimao at the second round, had qualified his Honda CBR600R on row 2 and was aiming for his second podium of the year.
The Italian rider's presence at the next round at Silverstone is doubtful.